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Clinical trials for First Molar

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    23 result(s) found for: First Molar. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2019-002114-38 Sponsor Protocol Number: KSL0118 Start Date*: 2019-09-04
    Sponsor Name:DOMPé FARMACEUTICI S.P.A.
    Full Title: Randomized, single dose, placebo-controlled, double-blind, parallel group study to evaluate the onset of pain response after administration of ketoprofen lysine salt 40 mg, in male and female subje...
    Medical condition: pain management in odontoiatry
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10062132 Tooth extraction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-003258-21 Sponsor Protocol Number: PDC-01-0205 Start Date*: 2022-05-19
    Sponsor Name:Cessatech A/S
    Full Title: Analgesic Efficacy and Pharmacokinetic-pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001 after Impacted Mandibular Third Molar Extraction
    Medical condition: Healthy male or female participants scheduled for surgical removal of an impacted mandibular third molar, where bone removal is judged to be needed.
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004865 10050327 Dental surgery NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004152-22 Sponsor Protocol Number: DEX-TRA-06 Start Date*: 2016-03-01
    Sponsor Name:MENARINI RICERCHE S.p.A.
    Full Title: Analgesic efficacy of oral dexketoprofen trometamol/tramadol hydrochloride versus tramadol hydrochloride/paracetamol: a randomised, double-blind, placebo and active-controlled, parallel group study...
    Medical condition: moderate to severe acute pain after removal of impacted lower third molar
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004867 10066714 Acute pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) ES (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022798-32 Sponsor Protocol Number: DEX-TRA 02 Start Date*: 2010-12-14
    Sponsor Name:Menarini Ricerche S.p.A.
    Full Title: DOUBLE-BLIND, RANDOMISED, PLACEBO AND ACTIVE CONTROLLED, PARALLEL GROUP STUDY TO EVALUATE THE ANALGESIC EFFECT OF A SINGLE ORAL ADMINISTRATION OF FOUR DIFFERENT COMBINATION DOSES OF DKP.TRIS WITH T...
    Medical condition: Severe pain following impacted third mandibular molar tooth extraction
    Disease: Version SOC Term Classification Code Term Level
    14.0 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) ES (Completed) HU (Completed) IT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2017-004655-23 Sponsor Protocol Number: CR4056-2-03 Start Date*: 2018-09-24
    Sponsor Name:Rottapharm Biotech s.r.l.
    Full Title: A randomized, double-blind, active- and placebo-controlled, parallel group, single dose, multicentre study to assess the analgesic effect of CR4056 in postoperative dental pain
    Medical condition: Postoperative dental pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10036276 Postoperative analgesia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-002245-42 Sponsor Protocol Number: UP-CLI-2019-002 Start Date*: 2020-11-13
    Sponsor Name:UNITHER Pharmaceuticals
    Full Title: A Comparative, Randomized, Double-blind, 3-arm parallel, Phase III Study to Evaluate the Efficacy and Safety of a Fixed Dose Combination of Nefopam/Paracetamol (tablet) Taken Orally in Moderate to ...
    Medical condition: Symptomatic short-term treatment of moderate to severe somatic pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed) BE (Completed) HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003323-11 Sponsor Protocol Number: ITIBU001 Start Date*: 2014-10-01
    Sponsor Name:"Sapienza" University of Rome
    Full Title: RANDOMIZED CLINICAL TRIAL, PLACEBO-CONTROLLED, SPLIT-MOUTH, A DOUBLE-BLIND, FOR THE EVALUATION OF THE EFFECTIVENESS OF PREemptive ANALGESIA BY ADMINISTRATION OF IBUPROFEN 400MG, FOR THE CONTROL ...
    Medical condition: POST-OPERATIVE ACUTE PAIN (DAPO)
    Disease: Version SOC Term Classification Code Term Level
    17.1 10017947 - Gastrointestinal disorders 10031009 Oral pain PT
    17.1 10017947 - Gastrointestinal disorders 10030973 Oral discomfort PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002996-32 Sponsor Protocol Number: 12UK/DCsc04 Start Date*: 2012-11-12
    Sponsor Name:IBSA Institut Biochimique S.A.
    Full Title: Preliminary evaluation of the efficacy and local tolerability of Injectable Diclofenac at 5, 12.5, 25 and 50 mg/mL, administered locally prior to surgery for the prevention of post-operative pain a...
    Medical condition: post-surgical pain after lower third molar removal.
    Disease: Version SOC Term Classification Code Term Level
    15.0 100000004863 10036286 Post-operative pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2015-005426-19 Sponsor Protocol Number: 51237 Start Date*: 2016-02-09
    Sponsor Name:Rigshospitalet, Copenhagen University Hospitals
    Full Title: "Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia in Patients following Recovery from Impacted Mandibular Third Molar Extraction. A Randomized, Placebo-controlled, ...
    Medical condition: Healthy volunteers (n = 94) are included. The main study includes 14 subjects who have had an uncomplicated, impacted mandibular, third molar extraction 4-5 weeks prior to participation in the stud...
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004867 10049475 Chronic pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000592-24 Sponsor Protocol Number: MR308-3501 Start Date*: 2017-03-15
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: A Randomized, Double-Blind, Multicenter, Placebo- and active Comparator-Controlled Study to evaluate Efficacy and Safety of MR308 in the Treatment of Acute Pain After Third Molar Tooth Extraction (...
    Medical condition: Acute pain after third molar tooth extraction; dental procedure must have involved extraction of at least two impacted third molars requireing bone removal. If only two impacted third molars are ex...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000023314 10066714 Acute pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-001586-27 Sponsor Protocol Number: SOMCT01-C Start Date*: 2014-07-25
    Sponsor Name:SOM Innovation Biotech SL (SOM Biotech)
    Full Title: Study of SOM0226 in familial amyloid polyneuropathy (FAP) patients and asymptomatic carriers to evaluate protein stabilization activity
    Medical condition: Patients with familial amyloid polyneuropathy (FAP), asymptomatic carriers and healthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004850 10057949 Familial amyloid polyneuropathy LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002136-15 Sponsor Protocol Number: 2008 AN02 Start Date*: 2010-01-25
    Sponsor Name:Ninewells Hospital and Medical School
    Full Title: A randomised single blind study comparing the molar ED50 of levobupivacaine and molar ED50 of ropivacaine when administered as a femoral perineural infusion for pain relief after total knee replace...
    Medical condition: Pain after total knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003398 Arthroplasty of knee LLT
    9.1 10036236 Postoperative pain relief LLT
    9.1 10024758 Local anaesthesia LLT
    9.1 10041536 Spinal anaesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023476-23 Sponsor Protocol Number: SPON766-09 Start Date*: 2011-03-17
    Sponsor Name:Cardiff University
    Full Title: Seal or Varnish? A Randomised Trial To Determine The Relative Cost And Effectiveness Of Pit And Fissure Sealants And Fluoride Varnish In Preventing Dental Decay
    Medical condition: Dental Caries
    Disease: Version SOC Term Classification Code Term Level
    13.1 10012318 Dental Caries LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005807-41 Sponsor Protocol Number: PRE-EMPTIVE Start Date*: 2013-04-28
    Sponsor Name:"Sapienza" University of Rome
    Full Title: RANDOMIZED CLINICAL TRIAL, PLACEBO-CONTROLLED, SPLIT-MOUTH, A DOUBLE-BLIND, FOR THE EVALUATION OF THE EFFECTIVENESS OF PRE-emptive ANALGESIA BY ADMINISTRATION OF PARACETAMOL 500MG + codeine 30mg, ...
    Medical condition: POST-OPERATIVE ACUTE PAIN (DAPO)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10031009 Oral pain PT
    14.1 10017947 - Gastrointestinal disorders 10030973 Oral discomfort PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004235-39 Sponsor Protocol Number: 20140929sketamine Start Date*: 2016-08-06
    Sponsor Name:Folktandvården, Landstinget Dalarna
    Full Title: Pain control in surgical intervention. Biomarkers in acute and chronical post operative pain
    Medical condition: Post operative pain
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10051059 Oral surgery PT
    19.0 10042613 - Surgical and medical procedures 10036237 Post operative analgesia LLT
    19.0 10042613 - Surgical and medical procedures 10036236 Postoperative pain relief LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004176-35 Sponsor Protocol Number: AH-09-10 Start Date*: 2015-06-26
    Sponsor Name:Pfizer
    Full Title: Evaluation Of The Efficacy Of A Novel Ibuprofen Formulation In The Treatment Of Post Surgical Dental Pain: Study I
    Medical condition: Post Surgical Dental Pain
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-002042-11 Sponsor Protocol Number: 3699 Start Date*: 2006-07-31
    Sponsor Name:Newcastle Upon Tyne Hospitals NHS Trust
    Full Title: “The efficacy of inferior alveolar nerve block and buccal infiltration for pulp anaesthesia in mandibular teeth”
    Medical condition: N/A. This work is of direct relevance to everyday general dental practice. The outcomes of this work are likely to influence the way in which paractitioners approach the problem of anaesthetising m...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-002220-37 Sponsor Protocol Number: UP-CLI-2020-001 Start Date*: 2021-02-24
    Sponsor Name:UNITHER Pharmaceuticals
    Full Title: Comparison of the analgesic effect of a new paracetamol formulation (paracetamol UNIFLASH) for buccal use and two different doses of an oral paracetamol form controlled versus placebo in patients s...
    Medical condition: Symptomatic short-term treatment of moderate pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017978-21 Sponsor Protocol Number: EMR700568-012 Start Date*: 2010-12-20
    Sponsor Name:Merck Serono S.A. - Geneva
    Full Title: Prospective observational long-term safety registry of Multiple Sclerosis patients who have participated in cladribine clinical trials (PREMIERE)
    Medical condition: Multiple Sclerosis patients who have participated in cladribine tablets clinical trials
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029205 - Nervous system disorders 10028245 Multiple sclerosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed) LT (Completed) AT (Completed) GR (Completed) CZ (Completed) GB (Completed) EE (Completed) LV (Completed) BE (Completed) SE (Completed) PT (Completed) DK (Completed) ES (Completed) IT (Completed) PL (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2021-000586-33 Sponsor Protocol Number: 19-PP-15 Start Date*: 2021-07-21
    Sponsor Name:CHU de Nice
    Full Title: Effect of molar sodium lactate infusion on cerebral hemodynamic in patients with severe subarachnoid hemorrhage: a multicenter double-blind randomized controlled study
    Medical condition: Subarachnoid hemorrhage caused by rupture of cerebral aneurysm
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004852 10042320 Subarachnoid hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
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